After weeks of weather delays, NASA astronauts finally set to depart space station

After weeks of delays due to inclement weather, three astronauts and a cosmonaut are finally set to leave the International Space Station on Wednesday, wrapping up an almost eight-month stint in orbit.

NASA astronauts Matthew Dominick, Michael Barratt and Jeanette Epps and Russian cosmonaut Alexander Grebenkin are scheduled to depart the space station at 5:05 p.m. ET, undocking from the orbiting outpost in their SpaceX Dragon capsule.

Their return flight was delayed multiple times. First, an undocking attempt Oct. 7 was called off because of Hurricane Milton, which made landfall in Florida as a Category 3 storm.

NASA and SpaceX have multiple designated splashdown zones for return flights, but all are located off the coast of Florida.

After the hurricane passed, the journey back to Earth was postponed several more times because of unfavorable weather at the splashdown sites, according to NASA. Stormy conditions and choppy seas not only pose problems for the capsule when it splashes down in the water, but can also be dangerous for the rescue teams who retrieve the astronauts and their spacecraft.

Even before the recent weather issues, Dominick, Barratt, Epps and Grebenkin had stayed in space longer than originally planned.

Their mission, called Crew-8, arrived at the International Space Station on March 5 and was initially scheduled to return to Earth in September. But their stint in orbit was extended so that their Dragon spacecraft could serve as an emergency lifeboat for two astronauts who flew to space aboard Boeing's Starliner capsule.

Issues with that spacecraft led NASA to bring the Starliner capsule back without a crew in early September. The astronauts who launched on it — Butch Wilmore and Sunita Williams — were originally expected to stay on the space station for just around a week, but are still there four months later. Had Crew-8 departed at the original time, that would have left astronauts without a way to get home should an urgent problem arise.

A separate mission, known as Crew-9, launched two crew members — NASA astronaut Nick Hague and Russian cosmonaut Aleksandr Gorbunov — to the space station on a SpaceX capsule late last month. That vehicle can fit four, so it had two empty seats, which will be used to bring Wilmore and Williams home. But they'll stay in space until the scheduled end of the Crew-9 mission in February.

Members of the group departing the space station Wednesday spent their time there conducting research, scientific experiments and assisting with visiting spacecraft, including the problem-plagued Starliner.

The trip home will take roughly 34 hours. The crew members are expected to splash down off the coast of Florida on Friday at around 3:30 a.m. ET.

NASA will air live coverage of the undocking process beginning at 3 p.m. ET.

This article was originally published on NBCNews.com